Analytical Data
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Gene name
RAB31
- Application
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Alternative Names
RAB31;RAB22B;Ras-related Protein Rab-31
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13636
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Expression Region
1-195aa
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AA Sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHLHKFLIWDTA GQERFHSLAP MYYRGSAAAV IVYDITKQDS FYTLKKWVKE LKEHGPENIV MAIAGNKCDL SDIREVPLKD AKEYAESIGA IVVETSAKNA INIEELFQGI SRQIPPLDPH ENGNNGTIKV EKPTMQASRR C
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Molecular Weight
26 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB31 is a member of the RAB family of small GTPases, which play crucial roles in intracellular membrane trafficking, signaling, and cytoskeletal organization. The study of RAB31 has garnered attention due to its involvement in various cellular processes and its potential implications in diseases, including cancer. Research indicates that RAB31 is implicated in the regulation of exocytosis and endocytosis, influencing how cells secrete and internalize molecules, thereby affecting cellular communication and homeostasis. Furthermore, recent studies have highlighted its role in the trafficking of specific proteins and organelles, suggesting that RAB31 might serve as a key regulator in the biogenesis of certain cellular structures. Given its involvement in these critical pathways, RAB31 has emerged as a promising target for therapeutic interventions, particularly in cancers where these processes become dysregulated. Understanding the functional dynamics of RAB31 and its molecular interactions through the use of recombinant protein techniques provides insight into its regulatory mechanisms and offers opportunities for exploiting its pathways for disease treatment. Consequently, the generation and characterization of recombinant RAB31 protein is crucial for elucidating its biological roles and therapeutic potential, paving the way for advancing our understanding of cellular function and pathology.
