Analytical Data
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Gene name
GATA5
- Application
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Alternative Names
GATA5；Transcription factor GATA-5
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BWX5
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Expression Region
1-397aa
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AA Sequence
MYQSLALAAS PRQAAYADSG SFLHAPGAGS PMFVPPARVP SMLSYLSGCE PSPQPPELAA RPGWAQTATA DSSAFGPGSP HPPAAHPPGA TAFPFAHSPS GPGSGGSAGG RDGSAYQGAL LPREQFAAPL GRPVGTSYSA TYPAYVSPDV AQSWTAGPFD GSVLHGLPGR RPTFVSDFLE EFPGEGRECV NCGALSTPLW RRDGTGHYLC NACGLYHKMN GVNRPLVRPQ KRLSSSRRAG LCCTNCHTTN TTLWRRNSEG EPVCNACGLY MKLHGVPRPL AMKKESIQTR KRKPKTIAKA RGSSGSTRNA SASPSAVAST DSSAATSKAK PSLASPVCPG PSMAPQASGQ EDDSLAPGHL EFKFEPEDFA FPSTAPSPQA GLRGALRQEA WCALALA
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Molecular Weight
41.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GATA5 is a member of the GATA family of transcription factors, which play crucial roles in various biological processes, including development, differentiation, and tissue homeostasis. During embryonic development, GATA5 is particularly important in cardiac and intestinal morphogenesis, as it regulates genes critical for these processes. Dysregulation of GATA5 expression has been implicated in various diseases, including congenital heart defects and certain types of cancer. Research has shown that GATA5 participates in the regulation of lineage specification and angiogenesis, making it a potential target for therapeutic interventions. The study of GATA5 recombinant proteins is essential for understanding its structure-function relationships, post-translational modifications, and interaction with other molecular partners in cellular pathways. By producing GATA5 as a recombinant protein, scientists can investigate its function in vitro, allowing for the detailed characterization of its enzymatic properties and the identification of binding partners, ultimately contributing to the elucidation of its role in both normal physiology and disease states. The ongoing research into GATA5’s mechanisms of action and its potential as a biomarker or therapeutic target highlights its importance in regenerative medicine and cancer therapy, thereby underscoring the significance of continued investigation in this area.
