Analytical Data
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基因名
CELA3A
- Application
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别名
CELA3A；ELA3；ELA3A；Chymotrypsin-like elastase family member 3A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P09093
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表达区间
29-270aa
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氨基酸序列
VVHGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISRDLTYQVVLGEYNLAVKEGPEQVIPINSEELFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASLPPAGDILPNKTPCYITGWGRLYTNGPLPDKLQQARLPVVDYKHCSRWNWWGSTVKKTMVCAGGYIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNFIWKPTVFTRVSAFIDWIEETIASH
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分子量
42.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CELA3A, or Chymotrypsin-like elastase family member 3A, is a serine protease that plays a crucial role in various physiological processes, including protein digestion and immune response regulation. Its expression is predominantly found in the pancreas, where it contributes to the breakdown of dietary proteins. Recent studies have highlighted the importance of CELA3A in various pathological conditions, including inflammatory diseases and certain cancers, due to its potential involvement in tissue remodeling and inflammation. Moreover, investigations into the structural characteristics of CELA3A have revealed its unique catalytic mechanisms and substrate specificity, making it an attractive target for drug development and therapeutic interventions. Researchers are increasingly focusing on the recombinant production of CELA3A to facilitate the study of its enzyme kinetics, biological functions, and interactions with other biomolecules. The ability to produce CELA3A in a controlled environment allows for detailed characterization and potential applications in biomedicine, such as developing protease inhibitors or enzyme replacement therapies. Understanding the functional properties and regulatory mechanisms of CELA3A is essential for elucidating its biological significance and exploring its potential as a biomarker or therapeutic target in various diseases.
