Analytical Data
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基因名
ISX
- Application
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别名
ISX;RAXLX;Intestine-specific homeobox
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q2M1V0
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表达区间
1-245aa
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氨基酸序列
MCAEVGPALCRGMERNSLGCCEAPKKLSLSFSIEAILKRPARRSDMDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEGRKSKRRVRTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGNLGAPQQLSEASVALPTNLDVAGPTWTSTALRRLAPPTSCCPSAQDQLASAWFPAWITLLPAHPWETQPVPGLPIHQTCIPVLCILPPPHPKWGSICATST
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分子量
43.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ISX (Interferon-stimulated gene X) is a key player in the immune response and has garnered significant attention in recent years due to its crucial role in regulating inflammation and immune signaling pathways. The study of ISX restructuring proteins has emerged from the recognition of their potential in therapeutic strategies against various diseases, including autoimmune disorders and cancers. Initial research highlighted ISX's capacity to modulate gene expression in response to interferons, which are critical components of the innate immune system. As scientists continued to investigate the molecular mechanisms governing ISX's function, they discovered various structural forms of the protein that could influence its activity and interactions with other cellular components. Understanding how these restructuring events occur and their implications for ISX's functionality is essential for developing targeted interventions. Moreover, given the rising prevalence of diseases associated with aberrant immune responses, ongoing research into ISX restructuring proteins aims to harness their properties for drug development and novel treatment modalities. The exploration of ISX’s structure-function relationship is paving the way for innovative approaches in immunotherapy, emphasizing the necessity of further investigations to elucidate the underlying biochemical pathways and their relevance to disease mechanisms.












