Analytical Data
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Gene name
C17orf66
- Application
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Alternative Names
HEATR9; C17orf66; Protein HEATR9; HEAT repeat-containing Protein 9
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A2RTY3
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Expression Region
1-570aa
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AA Sequence
MAYEKSTDIS DVSRSMFLYP WLEYPDKTKE LRKAMAPVHL PLSCYQMPKE EFPPSPECWR QHPSKPNSVP YCYFKKPEIY THWHDLYDQR EEREAEKMLR KMRDDCRYIK EVHQTHIKMF HLPMSKLTIK SEMRSRPLEP TQDPLKWQRL RELTKSLESP REDEQFYAAQ ALGCLRISDK FVMEALQQVA QTGPEKVKYE AYRTLAILGC LNKHVIRALI KQLKEKNEGQ RMETLTGLRM ALNSWAAVSK DKRTQVGDEG KLVPVLQTLI KKSSSEASLE AALCLGFLRP CSNMVQEFLL QCLCQGLKTQ RMKALRMLVK VMHVHSAPVI KAILDQLCSS SVLEDRFEAT QMLKTIGLEQ IQAQGLEELT FNLLRRKTHN EPFLAVRQAV AQTVEELKLK PTMMNLVEAQ LMNPDATARQ EAVISLGVLG IRSPQVFHLL LDLLDAENHQ AVKKSLQETL ILCASIDPWI QNKLKNKVLS VYEAPKTNVK AEPTRFQKEP ENPEELTIQD FRLAKLNPLF IAKSITKVGQ KKTPAFPPCC SKPRKHRPQV IGPWQPRIKK QLRVLAEIAK
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Molecular Weight
65.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C17orf66, also known as "Chromosome 17 Open Reading Frame 66," is a gene located on chromosome 17 that has garnered attention in recent years due to its potential role in various biological processes and disease mechanisms. Research has indicated that C17orf66 may be implicated in cellular functions such as apoptosis, autophagy, and signal transduction, making it a candidate for studying its effects on cancer progression and other diseases. The protein encoded by C17orf66 is believed to participate in the regulation of cellular stress responses and may interact with other proteins involved in key signaling pathways. Additionally, dysregulation of C17orf66 expression has been linked to neurodegenerative disorders and metabolic syndromes, highlighting its significance in both pathological and physiological contexts. Given the limited understanding of this protein's precise function and mechanisms, the production of recombinant C17orf66 protein has become a focus of research. By creating a robust, functional model of the protein, scientists aim to elucidate its roles at the molecular level, assess its interactions with other cellular components, and explore its potential as a biomarker or therapeutic target. This research could significantly enhance our understanding of C17orf66's contributions to health and disease, paving the way for innovative strategies in diagnosis and treatment.
