Analytical Data
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基因名
FGF8a
- Application
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别名
FGF8a；FGF19；Fibroblast growth factor
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P55075-2
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表达区间
23-204aa
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氨基酸序列
QHVREQSLVTDQLSRRLIRTYQLYSRTSGKHVQVLANKRINAMAEDGDPF AKLIVETDTFGSRVRVRGAETGLYICMNKKGKLIAKSNGKGKDCVFTEIV LENNYTALQNAKYEGWYMAFTRKGRPRKGSKTRQHQREVHFMKRLPRGHH TTEQSLRFEFLNYPPFTRSLRGSQRTWAPEPR
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分子量
21 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Fibroblast growth factor 8 (FGF8) is a member of the fibroblast growth factor family, which plays a critical role in embryonic development, cell differentiation, and tissue repair. FGF8 exists in multiple isoforms, with FGF8a being one of the most studied. This protein is known to participate in various biological processes, including limb and brain development, through its ability to interact with specific receptors and activate intracellular signaling pathways. Research into FGF8a has gained traction due to its implications in several pathological conditions, including cancer, where aberrant FGF signaling may promote tumor growth and metastasis. Additionally, FGF8a's role in neurogenesis and potential therapeutic applications in regenerative medicine have made it a focal point of scientific inquiry. The production of recombinant FGF8a has become essential for in vitro studies, enabling researchers to investigate its functional properties and therapeutic potential. These studies aim to elucidate the mechanisms by which FGF8a influences cellular behavior, thus providing insights that could lead to innovative treatments for diseases linked to dysregulated FGF signaling. Overall, the study of recombinant FGF8a not only enhances our understanding of developmental biology but also opens new avenues for targeted therapies in oncology and regenerative medicine.
