Analytical Data
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基因名
C20orf166
- Application
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别名
MIR1-1HG; C20orf166Uncharacterized Protein MIR1-1HG; MIR1-1 host gene Protein
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H1L0
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表达区间
1-177aa
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氨基酸序列
MPSCSCALMAPCGPAAGPAAVERTQQVARGEPGSARGQLQVSPEMSITHKEKENAHLKEILLFVNAEAFSQPQPHSAPVCEGQQLTGKFSTSVLTRAGGDASPCSWERLLCYGWSHC
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分子量
12.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C20orf166, also known as DFNB31, is a gene that has garnered considerable interest in the field of genetics and molecular biology due to its association with nonsyndromic hearing loss. Located on chromosome 20, C20orf166 encodes a protein believed to play a crucial role in the development and function of the auditory system. Mutations in this gene have been linked to autosomal recessive forms of hearing impairment, underscoring its importance in sensory biology. Recent studies have focused on the recombinant expression of C20orf166 to better understand its functional properties and mechanisms of action. Producing recombinant proteins allows for detailed biochemical analyses, including investigations into protein structure, interaction with other cellular components, and its role in cell signaling pathways relevant to hearing. Furthermore, understanding the molecular basis of C20orf166-related hearing loss may pave the way for novel therapeutic strategies aimed at restoring or enhancing auditory function. Consequently, research into C20orf166 and its recombinant protein offers valuable insights not only into the genetic basis of hearing loss but also into potential interventions that could improve outcomes for affected individuals.
