Analytical Data
-
Gene name
C20orf166
- Application
-
Alternative Names
MIR1-1HG; C20orf166Uncharacterized Protein MIR1-1HG; MIR1-1 host gene Protein
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9H1L0
-
Expression Region
1-177aa
-
AA Sequence
MPSCSCALMAPCGPAAGPAAVERTQQVARGEPGSARGQLQVSPEMSITHKEKENAHLKEILLFVNAEAFSQPQPHSAPVCEGQQLTGKFSTSVLTRAGGDASPCSWERLLCYGWSHC
-
Molecular Weight
12.9 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C20orf166, also known as DFNB31, is a gene that has garnered considerable interest in the field of genetics and molecular biology due to its association with nonsyndromic hearing loss. Located on chromosome 20, C20orf166 encodes a protein believed to play a crucial role in the development and function of the auditory system. Mutations in this gene have been linked to autosomal recessive forms of hearing impairment, underscoring its importance in sensory biology. Recent studies have focused on the recombinant expression of C20orf166 to better understand its functional properties and mechanisms of action. Producing recombinant proteins allows for detailed biochemical analyses, including investigations into protein structure, interaction with other cellular components, and its role in cell signaling pathways relevant to hearing. Furthermore, understanding the molecular basis of C20orf166-related hearing loss may pave the way for novel therapeutic strategies aimed at restoring or enhancing auditory function. Consequently, research into C20orf166 and its recombinant protein offers valuable insights not only into the genetic basis of hearing loss but also into potential interventions that could improve outcomes for affected individuals.
