Analytical Data
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基因名
RIBC1
- Application
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别名
RIBC1; RIB43A-like with coiled-coils protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N443
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表达区间
1-379 aa
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氨基酸序列
MYNIKQSTDT KEAAAIEARR NREKERQNRF FNVRNRVMGV DVQALNNQVG DRKRREAAER SKEAAYGTSQ VQYDVVVQML EKEEADRTRQ LAKKVQEFRE QKQQLKNGRE FSLWDPGQVW KGLPTYLSYS NTYPGPASLQ YFSGEDLDRD TRLRMQQGQF RYNLERQQQE QQQAKVDENY TDALSNQLRL AMDAQATHLA RLEESCRAAM MCAMANANKA QAAVQAGRQR CERQREQKAN LAEIQHQSTS DLLTENPQVA QHPMAPYRVL PYCWKGMTPE QQAAIRKEQE VQRSKKQAHR QAEKTLDTEW KSQTMSSAQA VLELEEQERE LCAVFQRGLG SFNQQLANEQ KAQQDYLNSV IYTNQPTAQY HQQFNTSSR
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分子量
44.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RIBC1 (Ribosome Initiation and Binding Protein 1) is a crucial protein that plays a significant role in ribosome biogenesis and translation regulation, which are vital processes in cellular growth and function. Recent studies have highlighted RIBC1's involvement in various physiological and pathological contexts, including cancer progression, neurodegenerative diseases, and cellular stress responses. The understanding of RIBC1’s structure and function is essential for elucidating its mechanisms of action and potential roles in disease. Researchers have been investigating RIBC1's interactions with other ribosomal proteins and translation factors, as well as its regulatory mechanisms at both the transcriptional and translational levels. The reconstitution of RIBC1 into recombinant forms has facilitated the exploration of its biological activity and interaction networks, leading to insights into how alterations in its expression or function may contribute to disease states. Comprehensive studies on RIBC1 could pave the way for novel therapeutic strategies aimed at targeting aberrant ribosomal function in various disorders, showcasing its potential as a biomarker for disease progression and a candidate for drug development.
