Cat: PA1000-5929

Recombinant Human CPLX2 Protein,His

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Analytical Data

  • 基因名

    CPLX2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CPLX2;Complexin-2

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q6PUV4

  • 表达区间

    1-134aa

  • 氨基酸序列

    MDFVMKQALGGATKDMGKMLGGEEEKDPDAQKKEEERQEALRQQEEERKAKHARMEAEREKVRQQIRDKYGLKKKEEKEAEEKAALEQPCEGSLTRPKKAIPAGCGDEEEEEEESILDTVLKYLPGPLQDMFKK

  • 分子量

    42.4kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CPLX2, or Complexin 2, is a protein predominantly expressed in the nervous system and plays a crucial role in synaptic transmission and neurotransmitter release. It is a member of the complexin family, which is involved in the regulation of SNARE (Soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex formation and stability, essential for vesicle fusion processes at synapses. Research on CPLX2 is gaining momentum due to its implications in understanding various neurological disorders, including synaptic dysfunctions linked to autism spectrum disorders, schizophrenia, and neurodegenerative diseases. The investigation of CPLX2 recombinant proteins has become increasingly significant, as such proteins are vital for elucidating the molecular mechanisms underlying synaptic regulation. By producing and studying CPLX2 in a recombinant system, researchers aim to explore its structural features, binding interactions with other synaptic proteins, and functional roles in neurotransmitter release. This research not only enhances our understanding of synaptic physiology but also opens avenues for developing therapeutic strategies targeting CPLX2-related pathologies. Overall, the study of CPLX2 recombinant proteins serves as a bridge between basic neuroscience and potential clinical applications, highlighting the importance of this protein in maintaining synaptic health and function.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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