Analytical Data
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Gene name
REG3B
- Application
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Alternative Names
REG3B；EXTL1L；EXTR1；KIAA0519；Exostosin-like 3
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Species
Mouse
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P35230
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Expression Region
1-175aa
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AA Sequence
MLPPTACSVM SWMLLSCLML LSQVQGEDSL KNIPSARISC PKGSQAYGSY CYALFQIPQT WFDAELACQK RPGGHLVSVL NSAEASFLSS MVKRTGNSYQ YTWIGLHDPT LGAEPNGGGW EWSNNDVMNY FNWERNPSTA LDRAFCGSLS RASGFLKWRD MTCEVKLPYV CKFTG
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Molecular Weight
18 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
REG3B, or Regenerating Islet-derived protein 3 beta, is a member of the Reg family of proteins, which are primarily produced in the pancreas and are implicated in various physiological and pathological processes. The study of REG3B has gained significant attention due to its role in the immune response, particularly in the context of inflammation and infection. In recent years, research has indicated that REG3B exhibits antimicrobial properties, contributing to the innate immune defense against bacterial pathogens. Additionally, REG3B is involved in the regeneration of pancreatic islet cells, making it a potential target for therapeutic strategies in diabetes and other metabolic disorders. Furthermore, its expression is modulated under various pathological conditions, including cancer, where it has been associated with tumor progression and metastasis. Investigating the mechanisms of REG3B function and its regulation may provide insights into its dual role in protective immunity and tissue regeneration, paving the way for developing novel therapeutic approaches in treating inflammatory diseases and improving islet function in diabetes.
