Analytical Data
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基因名
CPNE3
- Application
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别名
Copine 3; Copine III; Copine-3; Copine3; CopineIII; CPN3 ; CPNE 3; CPNE3; CPNE3_HUMAN; KIAA0636 ; PRO1071
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75131
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表达区间
1-537aa
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氨基酸序列
MAAQCVTKVALNVSCANLLDKDIGSKSDPLCVLFLNTSGQQWYEVERTERIKNCLNPQFSKTFIIDYYFEVVQKLKFGVYDIDNKTIELSDDDFLGECECTLGQIVSSKKLTRPLVMKTGRPAGKGSITISAEEIKDNRVVLFEMEARKLDNKDLFGKSDPYLEFHKQTSDGNWLMVHRTEVVKNNLNPVWRPFKISLNSLCYGDMDKTIKVECYDYDNDGSHDLIGTFQTTMTKLKEASRSSPVEFECINEKKRQKKKSYKNSGVISVKQCEITVECTFLDYIMGGCQLNFTVGVDFTGSNGDPRSPDSLHYISPNGVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPYCNGIQGIVEAYRSCLPQIKLYGQTNFSPIINHVARFAAAATQQQTASRYFVLLIITDGVITDLDETRQAIVNASRLPMSIIIVGVGGADFSAMEFLDGDGGSLHSPLGEVAIRDIVQFVPFRQFQNAPKEALAQCVLAEIPQQVVGYFNTYKLLPPKNPATKQQKQ
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分子量
84.81 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CPNE3 (Copine 3) is a member of the copine family of proteins, which are characterized by their two C2-like domains and a von Willebrand factor A (vWFA) domain. These proteins are known to be involved in various cellular processes, including calcium-dependent membrane interactions, signal transduction, and cytoskeletal organization. Emerging research has suggested that CPNE3 may play a critical role in neuronal development and function, as well as in the pathology of neurodegenerative diseases. The study of recombinant CPNE3 protein is essential for elucidating its biological functions and mechanisms of action. Researchers are particularly interested in its interaction with target proteins and membranes, as these interactions may reveal insights into the molecular pathways regulated by CPNE3. Furthermore, recombinant CPNE3 can serve as a valuable tool for studying its role in disease contexts, potentially leading to novel therapeutic strategies. Understanding the structure-function relationship of CPNE3 through recombinant protein studies could ultimately contribute to the development of targeted interventions for conditions associated with its dysregulation. Thus, the research on CPNE3 recombinant protein is not just pivotal for basic biology but also for its implications in translational research and therapeutic development.












