Analytical Data
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基因名
GATA2
- Application
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别名
GATA2；Endothelial transcription factor GATA-2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P23769
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表达区间
2-480aa
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氨基酸序列
(29 amino acid tag)EVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDV FFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPW LDGGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGG SGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSS AGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIP TYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVN CGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGT CCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRN RKMSNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAGHMAPVGHLPPFS HSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMGLEESGGGGSPGRRRRRR RRRRR
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分子量
50 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GATA2 is a zinc-finger transcription factor that plays a critical role in the regulation of various biological processes, including hematopoiesis, lymphocyte development, and angiogenesis. Mutations in the GATA2 gene have been associated with a range of hematological disorders, immune deficiencies, and congenital anomalies. Research into GATA2 recombinant proteins has gained significant attention due to their potential applications in understanding the molecular mechanisms underlying these conditions, as well as in therapeutic strategies. These recombinant proteins enable detailed studies of GATA2's functional domains, protein-protein interactions, and its role in gene regulation. Moreover, by exploring the effects of GATA2 mutations in a controlled environment, researchers aim to elucidate the pathways leading to disease. The generation of GATA2 recombinant proteins also facilitates the development of assays for drug screening and the design of targeted therapies, thereby contributing to advances in personalized medicine for patients suffering from GATA2-related disorders. As a result, the ongoing investigation into GATA2 recombinant proteins stands at the forefront of molecular biology and translational research, with implications for both fundamental understanding and clinical applications.
