Analytical Data
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基因名
GNB2L1
- Application
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别名
RACK1. GNB2L1. HLC7. PIG21
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P63244
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表达区间
1-317aa
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氨基酸序列
MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDIINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVTIGTR
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分子量
60.72 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GNB2L1, also known as the G protein beta 2-like protein 1, is a key player in cellular signaling pathways, primarily involved in regulating G protein-coupled receptor (GPCR) activity. Recent studies have highlighted its importance in various physiological processes, including neurotransmission, muscle contraction, and cell proliferation. Dysregulation of GNB2L1 has been implicated in several diseases, such as cancer and neurodegenerative disorders, making it a potential therapeutic target. The production of recombinant GNB2L1 protein facilitates detailed studies on its structural and functional characteristics, helping to elucidate its role in cell signaling. Furthermore, understanding the interactions between GNB2L1 and other signaling molecules can provide insight into the underlying mechanisms of diseases associated with its dysfunction. As researchers aim to develop targeted therapies, exploring the properties of this recombinant protein could pave the way for novel interventions in treating conditions linked to GPCR signaling. Additionally, GNB2L1's role in modulating G protein complexes indicates its potential as a biomarker for disease progression and response to therapy. The ongoing investigation of GNB2L1's properties promises to advance our knowledge of cellular signaling networks and may contribute to the development of precision medicine strategies in treating related disorders.
