Analytical Data
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Gene name
XTP3TPA
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简介
XTP3TPA protein crucially hydrolyzes deoxynucleoside triphosphates (dNTPs), particularly preferring dCTP and its analogs, like 5-iodo-dCTP and 5-methyl-dCTP. This selective hydrolysis, reflecting high efficiency, likely safeguards against the incorporation of genotoxic nucleotide analogs into DNA or RNA, contributing to genomic integrity and protecting cellular nucleotide pools. XTP3TPA Protein, Human (His) is the recombinant human-derived XTP3TPA protein, expressed by E. coli , with N-His labeled tag.
- Application
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Alternative Names
dCTP pyrophosphatase 1; dCTPase 1; RS21C6; DCTPP1; CDA03
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H773
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Expression Region
M1-T170
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Protein Length
Full Length
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Molecular Weight
19 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
XTP3TPA is a recombinant protein that has gained significant attention in recent years due to its potential applications in various fields, particularly in biotechnology and medicine. As an engineered protein, XTP3TPA is derived from specific genetic sequences that encode for functional domains known to interact with cellular pathways. Researchers have been particularly interested in its role in signal transduction, where it may influence cellular responses to external stimuli. The background for studying XTP3TPA lies in the increasing demand for targeted therapies in disease treatment, where precise modulation of biological processes is crucial. Moreover, the ability to produce XTP3TPA in a recombinant form enhances its availability and allows for easier manipulation in experimental settings. Understanding the biochemical properties and interactions of XTP3TPA can lead to advancements in drug development, particularly in designing therapeutics that can modulate its activity. Furthermore, there is a growing interest in its potential use as a biomarker in diagnostic applications, as its expression levels may correlate with specific pathological conditions. Overall, ongoing research into XTP3TPA serves to unravel its intricate functions, aiming to unlock its full potential in clinical and therapeutic applications.
