Analytical Data
-
基因名
UCMA
-
简介
UCMA proteins are key regulators of the complex control of osteogenic differentiation, particularly in the fetal cartilage periphery and at the cartilage-bone interface. Its involvement suggests a crucial role in negatively regulating osteochondral precursor cell differentiation. UCMA Protein, Human is the recombinant human-derived UCMA protein, expressed by E. coli , with tag free.
- Application
-
别名
Unique cartilage matrix-associated protein; UCMA; Gla-rich protein; C10orf49
-
种属
Human
-
表达系统
E. coli
-
标签
Tag Free
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q8WVF2
-
表达区间
S65-T138
-
蛋白长度
Full Length of Mature Protein
-
分子量
14 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UCMA (Uromodulin Cystatin-like Multimeric Alpha) is a novel multifunctional protein that has garnered significant attention in recent years due to its potential role in various biological processes, particularly in immune regulation and cell signaling. Initially discovered in the context of kidney function, UCMA is believed to be involved in modulating the immune response and maintaining tissue homeostasis. Research highlights its unique structure, which allows it to form multimeric complexes, enhancing its biological activities. Studies have shown that UCMA may play a protective role in inflammatory diseases and could be crucial in renal pathologies. Furthermore, its implications in the tumor microenvironment suggest that UCMA might influence cancer progression and metastasis, making it a potential target for therapeutic interventions. The exploration of UCMA as a recombinant protein for research purposes has opened new avenues for understanding its mechanisms of action and therapeutic applications, signaling a shift towards more targeted and effective treatment strategies in immunology and oncology. The ongoing investigation into UCMA's structure-function relationship and its interactions with other proteins continues to uncover its significance in health and disease, positioning UCMA as a promising candidate for future biotherapeutics and diagnostic tools.
