Analytical Data
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Gene name
Minor allergen Can f 2
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简介
The Minor allergen Can f 2 protein is found in tongue epithelial tissue and the parotid gland. Minor allergen Can f 2 protein, Dog (His-SUMO) is the recombinant dog-derived Minor allergen Can f 2 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.
- Application
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Alternative Names
Minor allergen Can f 2; Allergen Dog 2; allergen Can f 2
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Species
Dog
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Source
E. coli
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Tag
N-His;N-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O18874
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Expression Region
Q19-D180
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Protein Length
Full Length of Mature Protein
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Can f 2, a minor allergen derived from dog dander, is a significant protein implicated in allergic responses among sensitive individuals. It is part of a complex of proteins that can provoke allergic reactions in dog owners and others exposed to dogs. As the prevalence of pet ownership increases worldwide, understanding the allergens associated with domestic animals like dogs becomes increasingly important in allergology. The recombinant form of Can f 2 is particularly valuable for research and clinical purposes, as it allows for the detailed study of its structure, function, and immunogenic properties without the ethical and practical concerns associated with using animal-derived proteins. Researching Can f 2's recombinant protein not only aids in elucidating the mechanisms of allergy mechanisms but also holds promise for the development of more specific diagnostic tools and potential immunotherapy approaches. Its characterization offers insights into the allergenic potentials of household pets, leading to better management strategies for individuals suffering from pet-related allergies. With advancements in biotechnology, the production of recombinant Can f 2 facilitates the exploration of allergenicity and enhances our understanding of how to alleviate allergic reactions in sensitized individuals.
