Cat: IPD-X11310

Recombinant Cynomolgus IL-1 Rrp2 Protein (HEK293), C-8*His

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Analytical Data

  • 基因名

    IL-1 Rrp2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R

  • 种属

    Cynomolgus

  • 表达系统

    HEK293

  • 标签

    C-8*His

  • 纯度

    > 90% as determined by SDS-PAGE.

  • 蛋白编号

    EHH61702.1

  • 表达区间

    D20-R335

  • 蛋白长度

    Partial

  • 分子量

    60-70 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

IL-1 Rrp2, a member of the interleukin-1 receptor family, plays a crucial role in the immune response and inflammatory processes. It is primarily involved in mediating the effects of interleukin-1 (IL-1), a key cytokine that regulates various physiological and pathological functions, including fever, inflammation, and apoptosis. Understanding the structure and function of IL-1 Rrp2 is essential for elucidating its role in health and disease, particularly in conditions such as autoimmune disorders and chronic inflammatory diseases. Previous studies have demonstrated that the activation of IL-1 signaling pathways can lead to both protective and detrimental effects, making it a significant target for therapeutic intervention. The recombinant expression of IL-1 Rrp2 is vital for characterizing its biochemical properties and assessing its potential as a biomarker or therapeutic target. By producing recombinant protein, researchers aim to study the receptor's interactions with ligands and downstream signaling pathways, thereby gaining insights into the mechanisms underlying IL-1 related pathologies. Additionally, recombinant IL-1 Rrp2 can serve as a tool for developing novel drugs that modulate its activity, potentially leading to better treatments for diseases characterized by excessive inflammation and immune dysregulation. Given the critical importance of IL-1 Rrp2 in various biological processes, ongoing research into its recombinant form holds promise for advancing our understanding of immune regulation and improving therapeutic strategies for related diseases.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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