Cat: IPD-X31346

Recombinant Human PNLIP/Pancreatic lipase Protein,His

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Analytical Data

  • 基因名

    PNLIP/Pancreatic lipase

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CSH1; hCS-A; CSA; CSMT; Chorionic Somatomammotropin Hormone 1; Choriomammotropin

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 95% as determined by SDS-PAGE.

  • 蛋白编号

    Q6PF11

  • 表达区间

    Gln28~Phe192

  • 分子量

    25kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

PLA2G2E, or phospholipase A2 group IIE, is an important enzyme involved in various physiological processes, including inflammation, cell signaling, and membrane dynamics. As a member of the phospholipase A2 family, it catalyzes the hydrolysis of phospholipids, resulting in the release of arachidonic acid and lysophospholipids, which serve as precursors for bioactive lipid mediators. The enzyme's role in inflammatory responses and its potential involvement in various diseases, such as cancer and autoimmune disorders, have garnered significant interest from researchers. Studies have shown that PLA2G2E expression can be regulated by pro-inflammatory cytokines and is implicated in the pathogenesis of chronic inflammatory conditions. Furthermore, recombinant PLA2G2E protein has become a valuable tool for investigating its biochemical properties, substrate specificity, and regulatory mechanisms. The production of this protein through recombinant DNA technology enables detailed studies into its structure-function relationships and interactions with other cellular components. Understanding PLA2G2E's role in disease processes may also unveil potential therapeutic targets for modulating inflammation and other related conditions, making it a focal point in molecular biology and pharmacology research. As a result, ongoing studies aim to elucidate the biological significance of PLA2G2E, paving the way for innovative strategies in disease management and treatment.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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