Analytical Data
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基因名
Neurofascin
- Application
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别名
Neurofascin; NFASC; KIAA0756
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种属
Human
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表达系统
HEK293
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标签
C-hFc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O94856-12
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表达区间
I25-Q939
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蛋白长度
Partial
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Neurofascin is a member of the immunoglobulin superfamily and is predominantly expressed in the nervous system, playing a crucial role in the development and maintenance of the myelin sheath in peripheral and central nervous systems. It functions as a cell adhesion molecule, facilitating the interactions between neurons and glial cells. The study of recombinant neurofascin proteins has gained considerable attention due to their potential implications in understanding neurodevelopmental disorders and demyelinating diseases such as multiple sclerosis. By examining the structure-function relationship of neurofascin, researchers aim to elucidate the molecular mechanisms underlying neural connectivity and myelin stability. Furthermore, recombinant neurofascin can be utilized in therapeutic applications, including the development of strategies for enhancing nerve regeneration and repair after injury. The expression of neurofascin in various isoforms, particularly neurofascin-186 and neurofascin-155, highlights the complexity of its functions and regulatory mechanisms. Investigations into the signaling pathways activated by neurofascin interaction with its ligands are critical for deciphering its role in neuronal plasticity and signaling transduction in health and disease. Overall, the exploration of neurofascin recombinant proteins represents a promising frontier in neuroscience research, with the potential to provide insights into fundamental biological processes and novel therapeutic targets in neuropathological conditions.












