Analytical Data
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基因名
TSC22/TSC22D1
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简介
TSC22D1 protein, possessing RNA polymerase II binding activity, regulates apoptotic and cell proliferation processes. It is found in the cytoplasm and nucleus and expressed in multiple structures like the alimentary system and central nervous system. With ubiquitous expression observed, TSC22D1 likely regulates diverse cellular processes across tissues. TSC22/TSC22D1 Protein, Mouse (His) is the recombinant mouse-derived TSC22/TSC22D1 protein, expressed by E. coli , with N-His labeled tag.
- Application
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别名
TSC22 domain family protein 1; Cerebral protein 2; KIAA1994; TGFB1I4
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
NP_033392
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表达区间
M1-A143
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蛋白长度
Full Length
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The TSC22 (TSC22 Domain Family Member 1) gene, particularly its isoform TSC22D1, plays a significant role in various biological processes, including immune response, apoptosis, and cell differentiation. TSC22D1 is known to act as a transcriptional regulator, and it has been implicated in the modulation of inflammatory responses and the regulation of cell growth. Research has shown that TSC22D1 can influence numerous signaling pathways, making it a potential biomarker for certain diseases and therapeutic targets. Its expression is often associated with various conditions, including autoimmune diseases and cancers, highlighting its importance in pathological and physiological states. The study of recombinant TSC22/TSC22D1 proteins allows for a deeper understanding of their functional roles in cellular processes and disease mechanisms. By producing these proteins in a laboratory setting, researchers can investigate their structure, interactions with other molecules, and potential as drug targets, thus providing insights into novel therapeutic strategies for conditions linked to their dysregulation. As such, TSC22D1 represents a promising avenue for research in molecular biology and biomedical applications, warranting further exploration of its functions and implications in human health.
