Analytical Data
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Gene name
SEZ6/BSRP-C
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简介
The SEZ6/BSRP-C protein contributes significantly to cell-to-cell recognition and neuronal membrane signaling, playing a crucial role in fundamental processes of neural networks.SEZ6/BSRP-C is particularly important in balancing dendritic elongation and branching, which shapes the complex structure of neurons.SEZ6/BSRP-C Protein, Mouse (HEK293, His) is the recombinant mouse-derived SEZ6/BSRP-C protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
SEZ-6; SEZ6; BSRPC; BSRP-C
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Species
Mouse
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Source
HEK293
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Tag
C-8*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7TSK2
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Expression Region
L20-H922
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Protein Length
Extracellular Domain
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Molecular Weight
145-150 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The SEZ6/BSRP-C protein is a member of the seizure-related 6 (SEZ6) family, which has garnered attention due to its potential implications in neurological disorders and synaptic function. Research has indicated that SEZ6 proteins are involved in the regulation of neuronal development and synaptic transmission, making them critical for understanding the mechanisms underlying various neurodevelopmental and neuropsychiatric conditions. SEZ6 has been shown to interact with key signaling pathways and proteins, contributing to synaptogenesis and neurotransmitter release. Additionally, mutations or dysregulation of SEZ6 are linked to epilepsy and other seizure disorders, highlighting its relevance in both basic neuroscience and clinical research. Given its role in neuronal communication and health, the study of SEZ6/BSRP-C not only aims to elucidate its functional mechanisms at the molecular level but also seeks to explore its potential as a therapeutic target for mitigating the effects of neurological diseases. Understanding the structure and function of SEZ6/BSRP-C via recombinant protein studies may offer insights into synaptic integrity and lead to novel interventions in neurodevelopmental disorders. Therefore, research on this protein is vital for advancing our understanding of brain function and developing effective strategies for treating associated conditions.
