Analytical Data
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Gene name
IVNS1ABP
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简介
The IVNS1ABP protein is intricately involved in multiple cellular functions, including pre-mRNA splicing, aryl hydrocarbon receptor (AHR) pathway, F-actin organization, and protein ubiquitination. It binds to F-actin through Kelch repeats, thereby stabilizing actin filaments and thereby protecting cells from actin instability-induced cell death. IVNS1ABP Protein, Human (sf9) is the recombinant human-derived IVNS1ABP protein, expressed by sf9 insect cells , with tag free.
- Application
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Alternative Names
IVNS1ABP; Influenza virus NS1A-binding protein; NS1-BP; NS1-binding protein; Aryl hydrocarbon receptor-associated protein 3; Kelch-like protein 39
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Species
Human
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Source
Baculovirus
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y6Y0
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Expression Region
I2-F642
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
IVNS1ABP, or Interferon-inducible virus resistance protein 1A binding protein, is a significant protein that plays a critical role in the immune response to viral infections. Research on IVNS1ABP has gained momentum due to its potential implications in virology and therapeutic interventions against various viral diseases. Understanding the structure and function of this recombinant protein is essential as it may serve as a target for designing antiviral drugs or enhancing the efficacy of existing therapies. Additionally, IVNS1ABP has been implicated in various cellular processes, including apoptosis and inflammation, making it a valuable candidate for studying the interplay between viral pathogenesis and host immune responses. Recent studies have focused on the characterization of IVNS1ABP at the molecular level, utilizing advanced techniques such as X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy to elucidate its interactions with viral components. The recombinant production of IVNS1ABP allows for further exploration of its biological functions and potential applications in vaccine development and therapeutic strategies. As the threat of emerging viral diseases continues to rise, research on IVNS1ABP is crucial for advancing our understanding of viral-host interactions and developing novel approaches to combat viral infections.
