Analytical Data
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Gene name
MTCP1
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简介
The MTCP1 protein plays a crucial role in promoting the phosphorylation and activation of AKT1 and AKT2, two key members of the AKT family. It does this through specific interactions with AKT1 and AKT2, primarily through their PH (pleckstrin homology) domains. MTCP1 Protein, Human is the recombinant human-derived MTCP1 protein, expressed by E. coli , with tag free.
- Application
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Alternative Names
MTCP1; Protein p13 MTCP-1; p13MTCP1; Mature T-cell proliferation-1 type B1; MTCP-1 type B1
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Species
Human
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Source
E. coli
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P56278
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Expression Region
M1-D107
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Protein Length
Full Length
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of MTCP1 (Mammalian T-cell leukemia virus type 1 (MTLV-1) regulatory protein) has gained significant importance due to its potential implications in cancer biology and immunology. MTCP1 is encoded by the human T-cell leukemia virus type 1 (HTLV-1), which is known to cause adult T-cell leukemia/lymphoma (ATLL). The presence of MTCP1 has been linked to the transformation of T-cells, influencing their proliferation and survival, and contributing to the pathogenesis of hematological malignancies. Understanding the structure and function of MTCP1 is crucial, as it may offer insights into viral oncogenesis and immune evasion mechanisms. Previous research has shown that MTCP1 can interact with various cellular proteins and modulate signaling pathways, particularly those related to apoptosis and cell cycle regulation. By investigating the recombinant expression of MTCP1, researchers aim to elucidate its functional roles at a molecular level, which could ultimately lead to the development of targeted therapies for HTLV-1-associated diseases. The recombinant protein serves as a valuable tool in both basic and applied research, enabling the study of its interaction with host factors and its effect on T-cell behavior. Overall, research on MTCP1 is poised to contribute to a deeper understanding of viral infections and their links to cancer, thereby opening avenues for innovative therapeutic strategies.
