Analytical Data
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Gene name
GRM2
- Application
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Alternative Names
GPRC1B; MGLUR2
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Species
Human
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Source
Baculovirus
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Tag
His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q14416
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Expression Region
E19-G493
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GRM2, or metabotropic glutamate receptor 2, is a key player in the central nervous system, involved in modulating synaptic transmission and plasticity. Its dysregulation has been implicated in various neurological disorders, including schizophrenia, autism, and depressive disorders. As a G protein-coupled receptor (GPCR), GRM2 mediates its effects through complex signaling pathways, making it a potential target for therapeutic intervention. Research on GRM2 recombinant proteins has gained momentum due to advances in protein expression and purification techniques, allowing scientists to study its structure and function in detail. Understanding the functional dynamics of GRM2 is crucial for elucidating its role in neurobiology and developing targeted pharmacological agents. Additionally, the recombinant protein can be utilized in high-throughput screening assays to identify novel compounds that modulate GRM2 activity. Overall, GRM2 recombinant protein studies represent a significant frontier in neuropharmacology, offering insights into the receptor's mechanisms while paving the way for innovative treatments for related psychiatric disorders.
