Analytical Data
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Gene name
TRPC3
- Application
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Alternative Names
TRP3
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Species
Human
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Source
HEK293
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Tag
Flag
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13507
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Expression Region
R2-E836
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Protein Length
Partial
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TRPC3 (Transient Receptor Potential Channel 3) is a member of the TRP channel family, primarily involved in various cellular processes, including calcium influx, signal transduction, and sensory functions. Research has identified its crucial roles in neuronal signaling, immune responses, and cardiovascular functions. Given its importance, TRPC3 has garnered interest as a potential therapeutic target for various diseases, such as neurodegenerative disorders, cardiovascular diseases, and certain types of cancer. To investigate its roles further, researchers have focused on producing recombinant TRPC3 proteins, which facilitate detailed study of the channel's structure, function, and pharmacology. Recombinant proteins enable the examination of TRPC3 behavior in controlled environments, thus providing insights into its ion conduction properties and interaction with regulatory proteins. Such studies are vital for understanding TRPC3's specific mechanisms in pathophysiological conditions and for the development of TRPC3-targeted therapies. Advances in protein expression systems and purification techniques have significantly enhanced the ability to obtain functional TRPC3, paving the way for groundbreaking discoveries in ion channel research and potential clinical applications.
