Analytical Data
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Gene name
KIAA1279
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简介
KIAA1279 protein is crucial for organizing axonal microtubules, vital for axonal outgrowth and maintenance in both the peripheral and central nervous systems. Interacting with key proteins like KIF1B and STMN2, it likely participates in molecular mechanisms associated with axonal transport and dynamics, emphasizing its significance in orchestrating intricate processes essential for nervous system development. KIAA1279 Protein, Human (sf9) is the recombinant human-derived KIAA1279 protein, expressed by Sf9 insect cells, with tag free.
- Application
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Alternative Names
KIF-binding protein; Kinesin family binding protein; KIFBP; KBP
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Species
Human
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Source
Baculovirus
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Tag
Tag Free
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96EK5
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Expression Region
Q96EK5 (N-G&P, M1-T621)
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Protein Length
Full Length
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Molecular Weight
72 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIAA1279, a gene located on chromosome 1, has recently garnered attention in the field of molecular biology due to its potential roles in various cellular processes and diseases. Research indicates that KIAA1279 encodes a protein involved in signaling pathways critical for cell proliferation, differentiation, and apoptosis. Its expression levels have been found to correlate with certain cancers, suggesting a possible role in tumorigenesis and cancer progression. Furthermore, investigations into the functional properties of the KIAA1279 recombinant protein have revealed its interaction with key cellular proteins, which may influence pathways such as the cell cycle and immune response. Given its implications in both normal physiological processes and pathological conditions, KIAA1279 is positioned as a potential biomarker for cancer diagnosis and a target for therapeutic interventions. Ongoing studies are focused on elucidating the precise mechanisms of action of the KIAA1279 protein, which may provide insights into novel treatment strategies for cancers and other diseases where its dysregulation occurs. Thus, the exploration of KIAA1279 and its recombinant protein represents a significant area of research with implications for understanding disease mechanisms and developing targeted therapies.
