Analytical Data
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Gene name
SLC30A4
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简介
The SLC30A4 protein is a possible proton-coupled zinc ion antiporter that mediates zinc import, possibly into endocytic compartments. This activity modulates intracellular zinc levels and affects zinc transport in the endocytic pathway. SLC30A4 Protein, Human (sf9, His, Strep, FLAG) is the recombinant human-derived SLC30A4 protein, expressed by sf9 insect cells , with N-Strep, C-Flag, N-8*His labeled tag.
- Application
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Alternative Names
SLC30A4; Zinc transporter 4; ZnT-4; Solute carrier family 30 member 4
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Species
Human
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Source
Baculovirus
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Tag
C-Flag;N-StrepⅡ;N-8*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O14863
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Expression Region
A2-P429
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Protein Length
Full Length
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SLC30A4, also known as zinc transporter 4 (ZnT4), plays a crucial role in cellular zinc homeostasis, which is essential for numerous biological processes, including enzyme activity, gene expression, and cell signaling. Dysfunction of SLC30A4 has been implicated in various pathological conditions, such as neurological disorders and developmental abnormalities. Understanding the structure and function of the SLC30A4 protein is vital for gaining insights into its mechanisms of action and its potential as a therapeutic target. The recombinant expression of SLC30A4 allows for the investigation of its transport properties, regulation, and interaction with other cellular components in controlled environments. By producing the recombinant protein in suitable expression systems, researchers can analyze its biochemical properties, study its influence on zinc ion transport, and explore the implications of its malfunction in disease contexts. Furthermore, insights gained from SLC30A4 research contribute to the broader understanding of zinc transporters as a whole and their roles in maintaining cellular zinc levels, which are critical for overall health and cellular function.
