Analytical Data
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Gene name
MXRA8
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简介
The MXRA8 protein is a transmembrane regulator that may interact with the integrin ITGAV:ITGB3 to affect various signaling pathways. It inhibits osteoclastogenesis, promotes chondrogenesis, and stimulates the formation of primary cilia in chondrocytes. MXRA8 Protein, Human (HEK293, His) is the recombinant human-derived MXRA8 protein, expressed by HEK293 , with C-His labeled tag.
- Application
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Alternative Names
Adipocyte-specific protein 3; Adipocyte-specific 3; DICAM; Asp3; Limitrin
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Species
Human
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Source
HEK293
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Tag
C-8*His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BRK3-1
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Expression Region
V20-Q341
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Protein Length
Extracellular Domain
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Molecular Weight
40-53 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MXRA8, or Matrix remodeling-associated protein 8, is a novel receptor believed to play a significant role in immune response and cellular signaling. Recent studies have highlighted its potential importance in the context of viral infections, particularly as a receptor for various pathogens, including members of the coronavirus family. Researchers have shown that MXRA8 can facilitate the entry of certain viruses into host cells, making it a focal point for understanding viral pathogenesis and developing therapeutic strategies. Given its involvement in critical cellular processes, MXRA8 has emerged as a promising target for drug design and vaccine development. The production of recombinant MXRA8 protein is essential for elucidating its structure-function relationships and its interactions with viral particles and cellular partners. Through the study of MXRA8, scientists aim to better comprehend its role in both health and disease, potentially paving the way for innovative treatments for viral infections and related immune disorders. The ongoing research into MXRA8 underscores the growing interest in the interplay between matrix proteins and pathogen-host interactions, positioning MXRA8 as a key player in the broader field of immunology and virology.
