Analytical Data
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基因名
CYGB
- Application
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别名
HGB; STAP; Stellate Cell Activation-Associated Protein; Histoglobin
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 95% as determined by SDS-PAGE.
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蛋白编号
Q8WWM9
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表达区间
Met1~Pro190
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分子量
25kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Cytoglobin (CYGB) is an intriguing heme-containing globin that has garnered significant interest in recent research due to its potential roles in various physiological and pathological processes. Initially identified in the early 2000s, CYGB is expressed in multiple tissues, including the brain, liver, and lungs, suggesting a widespread functional significance. Unlike other globins, CYGB is thought to play a critical role in oxygen storage and regulation, redox homeostasis, and the response to hypoxic conditions. Its unique structure allows it to bind oxygen, nitric oxide, and reactive oxygen species, linking it to cellular signaling and cytoprotection mechanisms. Recent studies have illuminated its contributions to various diseases, including neurodegenerative disorders, ischemia, and fibrosis, by demonstrating how CYGB can modulate oxidative stress and inflammation. The recombinant production of CYGB has enabled researchers to explore its biochemical properties, interactions, and potential therapeutic applications, further establishing its importance in understanding cellular responses to stress and injury. As such, CYGB is positioned as a promising candidate for future interventions targeting oxidative damage and tissue repair, highlighting the necessity for continued exploration into its biology and therapeutic potential.












