Analytical Data
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基因名
Epigen
- Application
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别名
EPGN; Epithelial Mitogen Homolog
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UW88
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表达区间
Ala23~Lys110
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蛋白长度
Partial
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分子量
15kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Epigenetic modifications play a crucial role in regulating gene expression, influencing cellular functions, and driving developmental processes. These modifications, which include DNA methylation and histone modifications, can lead to heritable changes in gene activity without altering the underlying DNA sequence. In recent years, the study of epigenetic reprogramming has gained significant attention due to its potential implications in understanding complex biological systems, developmental biology, and disease mechanisms, particularly cancer. Researchers are increasingly focused on the development of epigenetic recombinant proteins, which serve as tools to manipulate epigenetic states in cells. By engineering proteins that can specifically target and modify epigenetic marks, scientists aim to elucidate the functional consequences of these modifications on gene regulation and cellular identity. The study of epigenetic recombinant proteins not only enhances our understanding of epigenetic regulation but also opens up new avenues for therapeutic intervention in various diseases linked to epigenetic dysregulation. Current research is exploring the design, production, and application of these proteins to foster breakthroughs in precision medicine, regenerative therapy, and the development of novel treatments for disorders where epigenetic reprogramming is a key factor.
