Analytical Data
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基因名
REG1A
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简介
REG1A Protein serves as an inhibitor of spontaneous calcium carbonate precipitation. REG1A Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived REG1A protein, expressed by HEK293 , with C-His labeled tag. REG1A Protein, Cynomolgus (HEK293, His), has molecular weight of ~19 & 21 kDa, respectively.
- Application
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别名
Lithostathine-1-alpha; ICRF; PSPS; PSPS1; REG
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种属
Cynomolgus
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表达系统
HEK293
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标签
C-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
G8F4F8
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表达区间
Q23-N166
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蛋白长度
Full Length of Mature Protein
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分子量
17&20 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
REG1A, also known as Regenerating Gene 1 alpha, is a member of the Reg family of proteins that plays a significant role in cellular regeneration and tumorigenesis. Initially identified for its upregulation in pancreatic tissues during acute injury, REG1A has garnered attention for its implications in various pathological processes, including cancer development and progression. Studies have shown that REG1A can promote cell proliferation and survival, making it a potential biomarker for pancreatic and other malignancies. Moreover, REG1A's regulatory effects on inflammation and tissue repair underscore its importance in both normal physiology and disease states. Research has indicated that REG1A can influence the tumor microenvironment, potentially impacting cancer cell behavior and therapeutic responses. This has prompted investigations into its role as a prognostic indicator and as a target for novel cancer therapies. The evolving understanding of REG1A’s multifaceted functions highlights its potential as a valuable focus for future research, particularly in delineating the mechanisms of tumor biology and developing innovative strategies for cancer management.
