Analytical Data
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Gene name
SP140L
- Application
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Alternative Names
SP140L; Nuclear body protein SP140-like protein
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9H930
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Expression Region
1-580aa
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Molecular Weight
74.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SP140L is a member of the SP140 family of proteins, which play crucial roles in the immune response and regulation of gene expression. Research into SP140L has gained momentum due to its potential involvement in various autoimmune diseases and as a modulator of inflammation. The protein is known to interact with chromatin and influence transcriptional activities, which makes it a key player in maintaining the balance of immune system homeostasis. Understanding the structure and function of SP140L is essential as it may provide insights into the mechanisms underlying immune dysregulation. Furthermore, the development of recombinant SP140L proteins has facilitated studies on its biochemical properties, interactions with other cellular molecules, and the identification of signaling pathways that it influences. This research not only enhances our comprehension of the roles of SP140L but also holds promise for therapeutic applications, particularly in designing targeted strategies for autoimmune diseases. As researchers continue to unravel the complexities of SP140L and its associated pathways, it may eventually lead to novel interventions aimed at correcting immune dysfunction and restoring proper immune responses.
