Analytical Data
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Gene name
DHDH
- Application
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Alternative Names
D-xylose 1-dehydrogenase D-xylose-NADP dehydrogenase Dimeric dihydrodiol dehydrogenase Hum2DD
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UQ10
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Expression Region
1-334aa
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Molecular Weight
63.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DHDH, or Dihydrolipoamide Dehydrogenase, is a key enzyme in metabolic pathways, particularly in the catalysis of the oxidative decarboxylation of alpha-keto acids. This enzyme plays a crucial role in cellular respiration and energy production by facilitating the regeneration of lipoamide, a vital cofactor in various enzymatic reactions. Research on DHDH has gained attention due to its association with several metabolic disorders and its potential implications in diseases such as diabetes and neurodegenerative conditions. The recombinant form of DHDH allows for detailed studies of its structure-function relationship, enzymatic mechanism, and interaction with substrates and inhibitors. By producing this protein in a controlled environment, researchers can investigate its biochemical properties, assess its stability, and explore its role in disease, potentially leading to novel therapeutic strategies. The recombinant DHDH is also valuable for biotechnological applications, including biosensors and enzyme replacement therapies. Understanding DHDH through recombinant protein research could provide deeper insights into metabolic regulation and the development of targeted interventions for related health issues.
