Analytical Data
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Gene name
PYK2
- Application
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Alternative Names
PKB; CADTK; CAKB; FADK2; FAK2; PTK; PTK2b; RAFTK; Calcium-dependent tyrosine kinase; Cell adhesion kinase beta; Focal adhesion kinase 2; Proline-rich tyrosine kinase 2
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Species
Mouse
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Source
E. coli
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Tag
N- His & GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9QVP9
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Expression Region
Ile704~Gly941
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Molecular Weight
57kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Pyk2 (proline-rich tyrosine kinase 2) is a non-receptor tyrosine kinase that plays a crucial role in various cellular processes, including cell adhesion, migration, and signaling. Investigating Pyk2 and its signaling pathways has garnered significant attention in recent years due to its essential functions in both normal cellular physiology and pathological conditions, such as cancer metastasis and neurodegenerative diseases. The protein is activated by various stimuli, including integrin engagement and growth factor receptor activation, leading to autophosphorylation and the recruitment of downstream signaling molecules. Recombinant Pyk2 protein is used extensively in biochemical and biophysical studies to elucidate its structure-function relationships, enzymatic activity, and interaction with other proteins. Understanding these mechanisms is vital for developing therapeutic strategies targeting Pyk2-related pathways. Moreover, the potential of Pyk2 as a biomarker for certain diseases highlights its importance in clinical research. Overall, the study of recombinant Pyk2 protein contributes significantly to our understanding of cellular signaling networks and their implications in health and disease.
