Analytical Data
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Gene name
PPP1R3B
- Application
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Alternative Names
PPP1R4; PTG; Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL; Protein phosphatase 1 regulatory subunit 4; Protein phosphatase 1 subunit GL
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q86XI6
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Expression Region
Met1~Tyr285
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Molecular Weight
36kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PPP1R3B, a member of the protein phosphatase 1 regulatory subunit family, plays a crucial role in modulating the activity of protein phosphatase 1 (PP1), a key enzyme involved in various cellular processes such as glycogen metabolism, cell division, and signal transduction. Research into PPP1R3B has gained momentum due to its implications in metabolic diseases, neurological disorders, and cancer. This protein is particularly important in the regulation of glycogen synthase kinase 3 (GSK3) and glycogen metabolism, making it significant for understanding conditions like diabetes and obesity. The ability of PPP1R3B to interact with other proteins and influence signaling pathways highlights its potential as a therapeutic target. Advances in recombinant protein technology have enabled scientists to produce and study PPP1R3B in detail, facilitating the exploration of its structure-function relationships and the identification of potential binding partners. These studies may provide insights into how dysregulation of PPP1R3B contributes to disease states and could pave the way for novel treatment strategies. Overall, continued investigation into the biochemical properties and cellular functions of PPP1R3B is essential for elucidating its role in health and disease.
