Analytical Data
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Gene name
PLIN3
- Application
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Alternative Names
M6PRBP1; TIP47; PP17; Mannose-6-Phosphate Receptor Binding Protein 1; Placental Protein 17; 47 kDa mannose 6-phosphate receptor-binding protein; Cargo selection TIP47
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Species
Human
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60664
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Expression Region
Glu134~Lys434
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Molecular Weight
37kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLIN3 (Perilipin 3), a member of the perilipin family, is crucial for lipid droplet dynamics and metabolism. It plays a pivotal role in the regulation of lipid storage and mobilization, influencing energy homeostasis in various cell types. Research has shown that PLIN3 is involved in the modulation of lipolysis and the overall function of adipocytes, as well as in the protective mechanisms against ectopic lipid accumulation and associated metabolic disorders. Moreover, its expression is linked to metabolic syndrome and obesity, making it a potential target for therapeutic interventions aimed at managing these conditions. The study of PLIN3 recombinant proteins is essential for understanding its structure-function relationships, facilitating the elucidation of its precise role in lipid metabolism. By producing recombinant PLIN3, researchers are able to investigate its interactions with other proteins, assess its impact on lipid droplet morphology, and explore how different post-translational modifications affect its function. This research is vital for uncovering potential pathways for drug development to combat obesity and related metabolic diseases.
