Analytical Data
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Gene name
ITF1
- Application
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Alternative Names
TCF3; E2A; VDIR; Transcription Factor 3; E2A Immunoglobulin Enhancer Binding Factors E12/E47; Transcription Factor E2-alpha; VDR Interacting Repressor
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P15806
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Expression Region
Ala421~Leu599
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Molecular Weight
30kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ITF1 (Immune Tolerance Factor 1) is a protein that plays a critical role in immune regulation and tolerance, making it a significant focus of research in immunology and therapeutic development. Understanding ITF1's function is essential for elucidating mechanisms underlying immune system disorders, such as autoimmune diseases and transplant rejection. Recent studies have indicated that ITF1 may influence immune cell differentiation and cytokine production, thereby shaping the immune response and preserving self-tolerance. The recombinant expression of ITF1 allows for detailed investigations into its structural and functional properties, enabling researchers to explore its potential as a biomarker for immune health and as a therapeutic target. Additionally, recombinant ITF1 can be used to develop novel immunotherapies aimed at modulating immune responses. As research progresses, the exploration of ITF1's interactions with other proteins and signaling pathways could provide further insights into its role in maintaining immune homeostasis and its implications in various diseases, paving the way for innovative treatment strategies.
