Cat: IPD-X38982

Recombinant Human SF1 Protein,His

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Analytical Data

  • 基因名

    SF1

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    ZFM1; ZNF162; BBP; Zinc Finger Protein 162; mBBP; Mammalian branch point-binding protein; Zinc finger gene in MEN1 locus; Transcription factor ZFM1

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q15637

  • 表达区间

    Ala2~Thr274

  • 分子量

    38kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

The SF1 (Steroidogenic Factor 1) protein, a member of the nuclear receptor superfamily, plays a critical role in the regulation of genes involved in steroidogenesis and reproductive function. Initially identified for its importance in the development of the adrenal and gonadal tissues, SF1 has garnered significant interest due to its implications in various physiological processes, including metabolism, reproductive health, and stress response. Research has revealed that SF1 functions as a crucial transcription factor, driving the expression of genes that are pivotal for the synthesis of steroid hormones such as cortisol and testosterone. Aberrations in SF1 signaling have been linked to clinical conditions, including adrenal insufficiency, infertility, and certain endocrine disorders. Additionally, studies suggest that SF1 may be involved in the pathogenesis of specific cancers, highlighting its potential as a therapeutic target. The development and characterization of recombinant SF1 proteins have enabled researchers to explore the protein's structure-function relationships, optimization of assay systems for drug discovery, and the identification of novel SF1 modulators. As our understanding of SF1 continues to expand, it opens avenues for innovative treatments and diagnostic approaches to manage related diseases effectively.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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