Analytical Data
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Gene name
Serum Albumin/ALB
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简介
The serum albumin/ALB protein has multiple binding abilities and can bind water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin, and drugs. Its main effects include regulating blood colloid osmotic pressure to achieve homeostasis. Serum Albumin/ALB Protein, Human (HEK293,His) is the recombinant human-derived Serum Albumin/ALB protein, expressed by HEK293, with C-His labeled tag.
- Application
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Alternative Names
Albumin; ALB; Serum albumin; ANALBA; FDAH; PRO0883; PRO0903; PRO1341
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Species
Human
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Source
HEK293
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Tag
C-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P02768-1
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Expression Region
D25-L609
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Protein Length
Full Length of Isoform-1 Mature Protein
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Molecular Weight
67-80 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Serum Albumin (ALB) is the most abundant protein in human blood plasma, playing a crucial role in maintaining oncotic pressure, transporting various substances, and regulating pH levels. Recombinant human serum albumin (rHSA) has gained significant attention in biomedical research and pharmaceutical applications due to its potential benefits over native albumin, including reduced risk of contamination with pathogens and improved safety profiles. The production of rHSA offers advantages such as enhanced stability, modified pharmacokinetics, and tailored pharmacodynamics, making it an attractive option for drug delivery systems, therapeutic agents, and as a plasma substitute in clinical settings. Research has focused on optimizing the expression and purification processes of rHSA, utilizing various recombinant systems such as bacterial, yeast, or mammalian cells to achieve high yields and functional purity. Understanding the structure-function relationships of rHSA is essential for developing effective treatments for a range of conditions, including liver cirrhosis, burns, and sepsis, where albumin levels are critically low. The ongoing studies seek not only to improve the production methods but also to explore innovative applications of rHSA in targeted drug delivery, as well as its potential role in regenerative medicine and as an immune modulator. This research aims to bridge the gap between basic science and clinical application, ultimately contributing to improved therapeutic strategies and patient outcomes.
