Analytical Data
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基因名
MIDN
- Application
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别名
Midnolin; Midbrain nucleolar protein; MIDN
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种属
Human
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表达系统
E. coli
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标签
C-6*His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q504T8
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表达区间
M1-A468
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氨基酸序列
MEPQPGGARSCRRGAPGGACELGPAAEAAPMSLAIHSTTGTRYDLAVPPDETVEGLRKRLSQRLKVPKERLALLHKDTRLSSGKLQEFGVGDGSKLTLVPTVEAGLMSQASRPEQSVMQALESLTETQVSDFLSGRSPLTLALRVGDHMMFVQLQLAAQHAPLQHRHVLAAAAAAAAARGDPSIASPVSSPCRPVSSAARVPPVPTSPSPASPSPITAGSFRSHAASTTCPEQMDCSPTASSSASPGASTTSTPGASPAPRSRKPGAVIESFVNHAPGVFSGTFSGTLHPNCQDSSGRPRRDIGTILQILNDLLSATRHYQGMPPSLAQLRCHAQCSPASPAPDLAPRTTSCEKLTAAPSASLLQGQSQIRMCKPPGDRLRQTENRATRCKVERLQLLLQQKRLRRKARRDARGPYHWSPSRKAGRSDSSSSGGGGSPSEASGLGLDFEDSVWKPEVNPDIKSEFVVA
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蛋白长度
Full Length
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分子量
60 kDa, based on SDS-PAGE under reducing conditions
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MIDN (Midline 1) is a protein that has drawn considerable attention in recent years due to its potential role in various biological processes and diseases. Initially identified as a midline morphogen in embryonic development, MIDN's function extends beyond developmental biology, influencing cellular differentiation and migration. Recent studies have implicated MIDN in the modulation of inflammatory responses, tumorigenesis, and neurodegenerative diseases, highlighting its potential as a therapeutic target. The reorganization of MIDN into recombinant proteins has become a focal point in research, allowing for detailed investigation of its structure-function relationships. By producing MIDN in a controlled environment, researchers aim to elucidate its interactions at the molecular level and assess its implications in pathological conditions. These efforts are critical for understanding how MIDN contributes to disease mechanisms and developing novel strategies for intervention. The advancement of recombinant DNA technology and protein expression systems has facilitated the production of MIDN derivatives, providing valuable tools for probing its biological significance and exploring potential applications in drug development and gene therapy. As research progresses, MIDN is poised to become a vital component in the formulation of innovative therapeutic approaches, underscoring the importance of continued exploration into its multifaceted roles in health and disease.
