Analytical Data
-
Gene name
AP3s2
- Application
-
Alternative Names
AP3S3; sigma3b; Sigma-adaptin 3b
-
Species
Human
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P59780
-
Expression Region
Met1~Val193
-
Molecular Weight
24kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AP3s2, or Adaptor Protein Complex 3 Sigma 2, plays a crucial role in the intracellular transport of proteins, especially in the sorting of membrane proteins within the trans-Golgi network and endosomes. Research on AP3s2 has garnered attention due to its involvement in the biogenesis of lysosome-related organelles and its potential links to various diseases, including neurological disorders and certain cancers. Mutations in the AP3S2 gene can lead to defects in the trafficking of proteins, resulting in cells that cannot properly regulate their internal environments. Understanding the structure and function of the AP3s2 protein is essential for elucidating its role in cellular mechanisms and its impact on human health. Advances in recombinant protein technology have enabled the production of AP3s2 in laboratory settings, facilitating detailed studies on its interactions with other proteins, its structural characteristics, and its functional pathways. Such studies are vital for the development of targeted therapies that address the underlying molecular disruptions caused by AP3s2-related pathologies. As research progresses, it is anticipated that the insights gained from AP3s2 studies will contribute significantly to the broader field of cell biology and the understanding of protein transport systems in health and disease.
