Analytical Data
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Gene name
ACCN4
- Application
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Alternative Names
ASIC4; BNAC4; Amiloride-sensitive cation channel 4, pituitary
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Species
Mouse
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Source
E. coli
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Tag
N-His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q7TNS7
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Expression Region
Pro372~Cys539
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Molecular Weight
22kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ACCN4, a member of the amiloride-sensitive cation channel family, plays a significant role in various physiological processes, including cellular signaling and ion homeostasis. Its unique properties make it a candidate for studying mechanosensation and osmoregulation. Research on ACCN4 has gained momentum due to its potential implications in understanding diseases such as hypertension and heart failure, where ion channel dysfunction can disrupt normal cellular function. Recombination techniques enable the production of ACCN4 in a laboratory setting, allowing for detailed study of its structure, function, and interactions with other cellular components. Such studies aim to elucidate the channel's mechanisms and regulatory pathways, ultimately contributing to the development of targeted therapies for related pathologies. Given the increasing interest in pharmacological modulations of ion channels, research on ACCN4 could provide insights into new therapeutic strategies, making it a valuable subject within the field of molecular biology and pharmacology.
