Analytical Data
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Gene name
IL-4
- Application
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Alternative Names
B-cell stimulatory factor 1
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Species
Human
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Source
E. coli
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Tag
N- His-SUMO
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P05112
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Expression Region
25-153aa
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Molecular Weight
31 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Interleukin-4 (IL-4) is a crucial cytokine primarily produced by activated T cells, mast cells, and basophils, playing a pivotal role in immune regulation and inflammation. Research into IL-4 has gained considerable attention due to its significant functions in promoting B cell differentiation, enhancing IgE production, and influencing the polarization of T helper cells towards a Th2 phenotype, which is associated with allergic responses and asthma. The recombinant form of IL-4 serves as a valuable tool in biomedical research, enabling the study of its signaling pathways and physiological effects. Furthermore, understanding IL-4's role in various diseases, such as allergies, asthma, and certain cancers, has opened avenues for therapeutic interventions. Researchers have been investigating IL-4's potential as a therapeutic agent in modulating immune responses and developing vaccines. The recombinant IL-4 protein can also serve as an essential component in the development of immunotherapies, aimed at harnessing the immune system to combat diseases. As such, the continued exploration of IL-4 and its recombinant form is integral for the advancement of both basic immunology and clinical applications.
