Cat: IPD-X39274

Recombinant Human SPINT2 Protein,His & GST

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Analytical Data

  • 基因名

    SPINT2

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    HAI2; Kop; PB; Placental Bikunin; Hepatocyte growth factor activator inhibitor type 2

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N- His & GST

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O43291

  • 表达区间

    Ala28~Lys197

  • 分子量

    49kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

SPINT2, or Serine Peptidase Inhibitor, is a member of the serine protease inhibitor family, which plays a critical role in regulating proteolytic enzymes involved in various physiological processes, including inflammation, cell proliferation, and apoptosis. Research surrounding SPINT2 has gained significant attention due to its potential implications in various diseases. For instance, studies have indicated that SPINT2 may have protective effects against pancreatic disorders and could be involved in the pathogenesis of certain cancers through its modulation of serine proteases. The protein's expression is found to be altered in several pathological conditions, making it a potential biomarker for disease states. Moreover, SPINT2 has been implicated in cardiovascular health, with evidence suggesting that it may influence vascular remodeling and response to injury. As such, recombinant SPINT2 protein is being investigated for its biochemical properties and therapeutic potential, as understanding its precise role in these processes could lead to novel treatment strategies. The production of recombinant SPINT2 allows for detailed studies of its structure-function relationship and interactions with proteases, paving the way for future research aimed at harnessing its inhibitory effects for clinical applications. Consequently, the exploration of SPINT2 as a therapeutic target or biomarker has opened new avenues in the fields of drug development and personalized medicine, highlighting its significance in both basic and applied biomedical research.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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