Analytical Data
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基因名
GPAM
- Application
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别名
GPAT1
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9HCL2
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表达区间
Leu594~Leu828
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分子量
31kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The study of GPAM (glycerol-3-phosphate acyltransferase) recombinant protein is rooted in the growing understanding of lipid metabolism and its implications in health and disease. GPAM is a key enzyme in the glycerolipid synthesis pathway, catalyzing the conversion of glycerol-3-phosphate into lysophosphatidic acid, which is a crucial step in the biosynthesis of triglycerides and phospholipids. Dysregulation of GPAM has been linked to various metabolic disorders, including obesity, diabetes, and cardiovascular diseases, highlighting its potential as a therapeutic target. Researchers are increasingly focused on producing recombinant GPAM to study its structure-function relationships, enzymatic activity, and regulatory mechanisms in detail. By utilizing recombinant DNA technology, GPAM can be expressed in host systems, allowing for the generation of large quantities of the protein for biochemical characterization and potential drug discovery. Additionally, understanding GPAM's role in lipid metabolism may offer insights into novel strategies for managing metabolic diseases, making it a significant area of research in molecular biology and pharmacology.
