Cat: IPD-X39492

Recombinant Human ZFHX4 Protein,His

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Analytical Data

  • Gene name

    ZFHX4

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    ZFH4; Zinc finger homeodomain protein 4

  • Species

    Human

  • Source

    E. coli

  • Tag

    N-His

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q86UP3

  • Expression Region

    Met1~Pro189

  • Molecular Weight

    24kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

ZFHX4, a member of the zinc finger homeobox (ZFH) family, plays a significant role in various biological processes, including embryonic development and cellular differentiation. Research into ZFHX4 has gained traction due to its potential implications in developmental disorders and various cancers. This protein is known for its transcriptional regulatory functions, influencing gene expression patterns critical for normal cellular function. Recent studies have suggested that ZFHX4 may be involved in the epithelial-mesenchymal transition (EMT), a crucial process in cancer metastasis. Furthermore, abnormalities in ZFHX4 expression have been linked to aggressive tumor phenotypes and poor patient prognosis. The recombinant expression of ZFHX4 enables researchers to investigate its functional mechanisms in detail, providing insights into its role in health and disease. The study of ZFHX4 not only enhances our understanding of developmental biology but also opens avenues for potential therapeutic interventions targeting its dysregulation in pathological conditions, making it a significant focus in molecular biology and oncology research.

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