Analytical Data
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基因名
GNg8
- Application
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别名
Guanine GNGT9; Nucleotide Binding Protein Gamma 8; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8
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种属
Mouse
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P63078
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表达区间
Met1~Leu70
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分子量
40kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The GNg8 recombinant protein is part of an expanding field of protein research aimed at understanding the complex interactions and functions of G-proteins in cellular signaling pathways. G-proteins play a crucial role in transmitting signals from various receptors on the cell surface to intracellular effector proteins, influencing numerous physiological processes. The GNg8 protein, in particular, is associated with G-protein coupled receptor (GPCR) signaling, which is vital for many biological responses, including sensory perception, immune responses, and neurotransmission. Studying GNg8 has garnered interest due to its potential implications in drug discovery and development, especially considering the role of GPCRs in various diseases, such as cancer, diabetes, and neurological disorders. By utilizing recombinant DNA technology, researchers can produce large quantities of the GNg8 protein, enabling detailed structural and functional analyses. These studies can lead to a better understanding of GNg8's role in signal transduction and its interactions with other cellular molecules. Overall, the investigation of GNg8 recombinant protein is pivotal for elucidating the mechanisms underlying G-protein mediated signaling, which could ultimately inform therapeutic strategies targeting GPCRs in various health conditions.
