Analytical Data
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基因名
WWC3
- Application
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种属
Human
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9ULE0
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表达区间
Asp230~Arg344
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分子量
17kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
WWC3 (World Wide Collaboration 3) is a member of the WWC protein family, characterized by the presence of WW domains that facilitate protein-protein interactions. This protein has garnered interest due to its potential roles in various cellular processes, including cell adhesion, signaling, and cytoskeletal dynamics. Recent studies have indicated that WWC3 may be involved in the regulation of the Hippo signaling pathway, which plays a crucial role in controlling cell growth, proliferation, and apoptosis. Dysregulation of this pathway is linked to several cancers and other diseases, highlighting the importance of understanding WWC3's function. Additionally, WWC3 is known to interact with key signaling molecules such as Yes-associated protein (YAP) and TAZ, which are effectors of the Hippo pathway. Investigating the mechanistic pathways and interactions of WWC3 can provide valuable insights into its role in normal cellular physiology and its implications in pathological conditions. Furthermore, as research into WWC3 continues to evolve, it holds promise for identifying novel therapeutic targets and strategies in cancer treatment and regenerative medicine. The increasing emphasis on the functional analysis of WWC3, alongside advancements in molecular biology techniques, underscores the importance of this protein in contemporary biomedical research.
