Analytical Data
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基因名
Ascl2
- Application
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别名
Mash2
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种属
Mouse
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O35885
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表达区间
1-263aa
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分子量
32.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Ascl2, or Achaete-Scute Family BHLH Transcription Factor 2, is a key transcription factor involved in neurogenesis and the regulation of stem cell differentiation. It plays a critical role in the development of the central nervous system and has been implicated in various cellular processes, including the maintenance of pluripotency and the promotion of neuronal lineage commitment. Research has shown that Ascl2 is essential for the proper formation of neural progenitor cells, influencing their proliferation and differentiation. Due to its significant biological functions, there is increasing interest in the study of Ascl2 recombinant proteins to explore their structural and functional properties. Recombinant Ascl2 protein can be produced through biotechnological methods, providing a valuable tool for investigating its molecular interactions and mechanisms of action at the cellular level. Understanding the precise role of Ascl2 and its associated pathways could lead to potential therapeutic applications in regenerative medicine and the treatment of neurodevelopmental disorders. Furthermore, elucidating the structure-function relationship of Ascl2 through recombinant protein studies can aid in the design of novel drugs or biomolecules that target its pathways, paving the way for innovative approaches in treating diseases linked to neural development and dysfunction.
