Analytical Data
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基因名
CDC25C
- Application
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别名
Dual specificity phosphatase Cdc25C
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种属
Human
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表达系统
E. coli
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P30307
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表达区间
1-473aa
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分子量
57.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CDC25C is a crucial member of the CDC25 phosphatase family, known for its role in regulating the cell cycle by activating cyclin-dependent kinases (CDKs). This protein is particularly important during the G2/M transition of the cell cycle, where it dephosphorylates and activates CDK1, facilitating mitotic entry. Dysregulation of CDC25C has been implicated in various cancers, making it a significant target for therapeutic interventions. Research on recombinant CDC25C protein aims to elucidate its structural and functional properties, providing insights into its enzymatic activity and regulatory mechanisms. By producing and characterizing this protein in vitro, scientists can study its interaction with other cell cycle regulators, investigate its role in tumorigenesis, and potentially explore its utility as a biomarker or therapeutic target in cancer treatment. Understanding the dynamics of CDC25C not only enhances our comprehension of cell cycle control but also opens avenues for developing novel cancer therapies that can selectively target proliferating cells with aberrant CDC25C activity.
